Preparing accurate cumulative antibiograms – some pointers – part 1

Preparation of cumulative antibiograms that describe local bacterial susceptibility patterns is an essential requirement for sensible empirical antibiotic prescribing and guideline development. Over coming weeks, I will share learnings from Australia where all hospitals are compiling antibiograms that are in accord with the CLSI M39-A2 Guideline and an Australian format for standardised antibiograms that is based on M39.

 Some important over-riding issues include:

  • Selection of specimen results that are reliable – exclusion of mixed cultures and likely contaminants
  • Assessment of the quality of antimicrobial susceptibility testing – see this brief question guide.
  • Exclusion of repeat same species isolates samples from the same person within a one year interval
  • Correct selection of the antibiotics that are tested (as per CLSI or EUCAST current guidelines) and reported in the antibiogram
  • Expression of % susceptible rather than % resistant with the number tested displayed against each antibiotic
  • Exclusion of species where < 30 isolates have been tested
  • Eventual stratification of specimens by whether they have a community versus healthcare-associated origin

About mdjkf

Microbiologist and Infectious Diseases Physician
This entry was posted in A/m resistance, Microbiology and tagged , , , . Bookmark the permalink.

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