Selected papers that related to COVID-19 infection prevention and control from the daily COVID-19 Critical Intelligence Unit listings and other identified literature. This posting does not assess the specific evidence or its quality. Please let me know of any gaps – @mdjkf.
Wilson et al. JHI. What is the evidence that medical procedures which induce coughing or involve respiratory suctioning are associated with increased generation of aerosols and risk of SARS-CoV-2 infection? A rapid systematic review. “There was an absence of evidence to suggest that the procedures included in the review were associated with an increased risk of transmission of respiratory infection.”
Deol et al, PLOS ONE. Estimating ventilation rates in rooms with varying occupancy levels: Relevance for reducing transmission risk of airborne pathogens . “..demonstrate two methods that can be used to estimate ventilation rate in busy congregate settings, such as clinic waiting rooms.”
- Gregson et al, Endoscopy. Identification of the source events for aerosol generation during oesophago-gastro-duodenoscopy. “Coughing was evoked in 60% of the endoscopies, with a greater peak concentration and a greater total number of sampled particles than the patient’s reference voluntary coughs (11 710 vs 2320 L−1 and 780 vs 191 particles, n=9 and p=0.008). Endoscopies with coughs generated a higher level of aerosol than tidal breathing, whereas those without coughs were not different to the background. “
- Deng et al medRxiv. Viral infection and transmission in a large well-traced outbreak caused by the Delta SARS-CoV-2 variant. “…first local transmission of the Delta SARS-CoV-2 variant in mainland China. All 167 infections could be traced back to the first index case.” Relevant to the current NSW situation; high presymptomatic viral loads and transmission’ 1000-fold higher viral loads seen than previous strain
- Wang et al. medRxiv. Comparative evaluation of the transmissibility of SARS-CoV-2 variants of concern.
- Ferris et al. Authorea. FFP3 respirators protect healthcare workers against infection with SARS-CoV-2 . Important observational evidence from Cambridge in the setting of rampant spread of B.1.1.7 (Alpha variant). “After the change in respiratory protection, cases attributed to ward-based exposure fell significantly, with FFP3 respirators providing 31-100% protection (and most likely 100%) against infection from patients with COVID-19.”
Grout et al. MJA. Estimating the failure risk of quarantine systems for preventing COVID-19 outbreaks in Australia and New Zealand . Good lessons from this analysis!
Coleman et al. medRxiv. Viral Load of SARS-CoV-2 in Respiratory Aerosols Emitted by COVID-19 Patients while Breathing, Talking, and Singing. The largest proportion of SARS-CoV-2 RNA copies was emitted by singing (53%), followed by talking (41%) and breathing (6%). Overall, fine aerosols constituted 85% of the viral load detected in our study. Virus cultures were negative. Singapore 2021 data ; most patients had VOC infections though only one with Delta.
- Wark et al MJA. We are not doing enough to prevent the spread of COVID-19 and other respiratory viruses in Australian hospitals.
- McMorrow CDC (USA). Improving communications around vaccine breakthrough and vaccine effectiveness. USA vaccine efficacy evidence in setting of Alpha and Delta variants. “Risk of severe disease or death reduced 10-fold or greater in vaccinated and Risk of infection reduced 3-fold in vaccinated.”
- Wei et al. JAMA. Nine Lessons Learned From the COVID-19 Pandemic for Improving Hospital Care and Health Care Delivery. Wisdom from New York’s experience.
Hyde et al. MJA. Australia must act to prevent airborne transmission of SARS‐CoV‐2.