Here is an example comment from Pathology North which is added to positive blood culture reports when a Gram negative coliform species ( Enterobacteriacae eg. E. coli) has been isolated:
The comment’s rationale is to promote short course treatment and also to prompt oral antibiotic switching in a timely manner. It also prompts consideration of source control, an important issue in all patients with sepsis. There are no data that establish a minimum duration for IV therapy. Endocarditis and other metastatic complications are extremely rare with these species, contrasting with bacteraemia due to Staphylococcus aureus where prolonged high dose IV therapy is predicated on this risk.
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