Category Archives: Bacteria (GNEG)

Gram negative pathogens

Burkholderia pseudomallei review including laboratory aspects

Guest posting: Dr Ian Marr, Microbiology Registrar, Pathology North. Melioidosis is a cause of severe pneumonia, bacteraemia, urosepsis, prostatic abscess, CNS infection, pyogenic myositis and liver and spleen abscesses. It is found in PNG especially around the Balimo region – … Continue reading

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Pertussis – diagnosis, outbreaks and incidence

Culture appearances – see the Atlas – bisected pearl appearance of the colonies on charcoal agar. Diagnostic pointers – Diagnosis of pertussis Outbreak literature – local studies – Pertussis outbreak PNG 2012, PNG medical journal 1977 report on pertussis outbreak.  Earlier report from Highlands … Continue reading

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Laboratory assays for diagnosis of tick-borne infections

Excellent overview by the Australian expert, Stephen Graves that is highly relevant to all countries, not just Australia. Professor Graves has been responsible for ground-breaking discoveries in this area and has much wisdom to impart. The incidence of rickettsial disease and … Continue reading

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Fatal case of meningococcal infection – a salutary tale

Originally posted on AIMED – Let's talk about antibiotics:
This unfortunate 27 year old pregnant woman collapsed at home with a seizure and then died soon after.  She had a disseminated W135 serotype infection – this serotype has been associated…

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Must know Gram negative pathogens for medicine and pathology registrars/residents

By focusing your study on these organisms first, you will gain knowledge that is generalisable across most less common pathogens and diseases. Be systematic in your study – see proforma. Enterobacteriaceae : E. coli, Klebsiella sp, Proteus sp, Enterobacter sp,  Salmonella … Continue reading

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Helicobacter pylori antibiotic resistance dilemmas and key questions

Originally posted on AIMED – Let's talk about antibiotics:
Helicobacter pylori infection is thought to be the most common bacterial infection worldwide. Whilst the prevalence of H. pylori is decreasing rapidly in Europe, Australia and the USA, where on average 10-15% of…

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Case report (from AAC): Community-Acquired Pyelonephritis in Pregnancy Caused by KPC-Producing Klebsiella pneumoniae

Abstract (full case report with expert commentary is free) Carbapenem-resistant Enterobacteriaceae (CRE) usually infect patients with significant comorbidities and health care exposures. We present a case of a pregnant woman who developed community-acquired pyelonephritis caused by KPC-producing Klebsiella pneumoniae. Despite … Continue reading

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