“UTI” – Requiem for a Heavyweight – a landmark paper

A really important paper to consider closely – i will send on a PDF via email as general access not available.  This editorial from the BMJ is a worthwhile read as well.

AIMED - Let's talk about antibiotics

A recent paper, “Urinary Tract Infection”-Requiem for a Heavyweight  by Dr Thomas Finucaine skillfully unpacks many key issues, coupling this with a consideration of the emerging knowledge of the urinary microbiome and virome, suggesting that the term “UTI” might better be referred to as a “urinary dysbiosis”.  The paper is worth a detailed read – here is the start of the abstract –

“Urinary tract infection” (“UTI”) is an ambiguous, expansive, overused diagnosis that can lead to marked, harmful antibiotic overtreatment. “Significant bacteriuria,” central to most definitions of “UTI,” has little significance in identifying individuals who will benefit from treatment. “Urinary symptoms” are similarly uninformative. Neither criterion is well defined. Bacteriuria and symptoms remit and recur spontaneously. Treatment is standard for acute uncomplicated cystitis and common for asymptomatic bacteriuria, but definite benefits are few. Treatment for “UTI” in older adults with delirium and bacteriuria is widespread but no evidence supports…

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About mdjkf

Microbiologist and Infectious Diseases Physician
This entry was posted in Journal, Module - Urinary Tract and tagged , , . Bookmark the permalink.

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