Category Archives: Microbiology

Invasive pneumococcal disease – the impetus for immunisation

Invasive Pneumococcal Disease Surveillance (Australia) – recent report gives you a good idea of which serotypes of pneumococcus are within the different vaccines and the recent changes to serotype-specific IPD indidence – we are seeing quite an impact that is … Continue reading

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Pertussis – diagnosis, outbreaks and incidence

Culture appearances – see the Atlas – bisected pearl appearance of the colonies on charcoal agar. Diagnostic pointers – Diagnosis of pertussis Outbreak literature – local studies – Pertussis outbreak PNG 2012, PNG medical journal 1977 report on pertussis outbreak.  Earlier report from Highlands … Continue reading

Posted in Bacteria (GNEG), Module-Respiratory infections, Nepal, PNG | Tagged | 1 Comment

Online microbe atlas- Gram stain and culture plate photos

This resource provides free to air photos of great quality-just the thing for your presentations and learning. http://microbe-canvas.com/Bacteria/gram-positive-cocci/streptococci/catalase-negative/beta-hemolysis/pyrase-positive-2/streptococcus-pyogenes.html

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Microbial Genomics for Public Health and Clinical Microbiology- Nov 2016 symposium report

This recent symposium was a great wrap up of whole genome sequencing at its many applications organised by the Doherty Institute in Melbourne.  Here is my (short) Doherty-symposium report which will give you some idea of where things are going- a rapidly developing … Continue reading

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Human Intestinal Microbiome in Health and Disease – recent short NEJM review

Short interesting review of this cutting edge topic for your December delectation!    “Human-associated microbes have primarily been viewed through the lens of a single species and its environment. Advances in culture independent technologies have shown the enormous diversity, functional … Continue reading

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Tuberculosis- drug resistant- online learning, mailing lists and references

Courtesy of Dr Suman Majumdar, Dr Catherine Berry and others. Therapeutics Recent presentation from our advanced trainee registrar concerning the new TB drugs: Brian_Chong 2017 New TB drugs. TB drug monographs :  up-to-date clinical profiles of TB drugs including guidance on … Continue reading

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Zika transmission prevention not just for men- updated WHO guidance

As well- Zika and risk of microcephaly – see this NEJM report.

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BCG vaccine – more than just protection from childhood tuberculosis

This is a useful BCG systematic review concerning childhood protection against TB- worth reading in detail. Longterm BCG protection into adulthood – vaccine efficacy (VE) 10-19 years post BCG was 58% (95% CI 27 to 76) p=0·002 and there was still a non-significant … Continue reading

Posted in Module- Mycobacteria, Mycobacteria tuberculosis, Public health | Tagged | 1 Comment

Molecular microbiology – recent tutorial references and resources

Basics DNA extraction – essential first step. Quantity of DNA obtained can be assayed spectrophotometrically. Reverse transcriptase step – for detection of RNA viruses Nucleic acid amplification –  know how PCR works! This PCR animation is easy to understand.  Many other … Continue reading

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Metapneumovirus (hMPV) – bug of the week

Human-metapneumovirus-sept-2016-path-north summary sheet. See also this local case reports of severe pneumonia due to hMPV.  Includes discussion of Hunter New England region, NSW,  Australia epidemiology and current knowledge / research in to hMPV. Note the change to taxonomy that has occurred in … Continue reading

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