Category Archives: Bacteria (GNEG)

Gram negative pathogens

Burkholderia pseudomallei review including laboratory aspects

Guest posting: Dr Ian Marr, Microbiology Registrar, Pathology North. Melioidosis is a cause of severe pneumonia, bacteraemia, urosepsis, prostatic abscess, CNS infection, pyogenic myositis and liver and spleen abscesses. It is found in PNG especially around the Balimo region – … Continue reading

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Pertussis – diagnosis, outbreaks and incidence

Culture appearances – see the Atlas – bisected pearl appearance of the colonies on charcoal agar. Diagnostic pointers – Diagnosis of pertussis Outbreak literature – local studies – Pertussis outbreak PNG 2012, PNG medical journal 1977 report on pertussis outbreak.  Earlier report from Highlands … Continue reading

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Laboratory assays for diagnosis of tick-borne infections

Excellent overview by the Australian expert, Stephen Graves that is highly relevant to all countries, not just Australia. Professor Graves has been responsible for ground-breaking discoveries in this area and has much wisdom to impart. The incidence of rickettsial disease and … Continue reading

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Fatal case of meningococcal infection – a salutary tale

Originally posted on AIMED – Let's talk about antibiotics:
This unfortunate 27 year old pregnant woman collapsed at home with a seizure and then died soon after.  She had a disseminated W135 serotype infection – this serotype has been associated…

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Must know Gram negative pathogens for medicine and pathology registrars/residents

By focusing your study on these organisms first, you will gain knowledge that is generalisable across most less common pathogens and diseases. Be systematic in your study – see proforma. Enterobacteriaceae : E. coli, Klebsiella sp, Proteus sp, Enterobacter sp,  Salmonella … Continue reading

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Case report (from AAC): Community-Acquired Pyelonephritis in Pregnancy Caused by KPC-Producing Klebsiella pneumoniae

Abstract (full case report with expert commentary is free) Carbapenem-resistant Enterobacteriaceae (CRE) usually infect patients with significant comorbidities and health care exposures. We present a case of a pregnant woman who developed community-acquired pyelonephritis caused by KPC-producing Klebsiella pneumoniae. Despite … Continue reading

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