Category Archives: Microbiology

Human Intestinal Microbiome in Health and Disease – recent short NEJM review

Short interesting review of this cutting edge topic for your December delectation!    “Human-associated microbes have primarily been viewed through the lens of a single species and its environment. Advances in culture independent technologies have shown the enormous diversity, functional … Continue reading

Posted in Microbiology, Module-basic microbiology and AMR | Tagged | Leave a comment

Tuberculosis- drug resistant- online learning, mailing lists and references

Courtesy of Dr Suman Majumdar, Dr Catherine Berry and others. Therapeutics Recent presentation from our advanced trainee registrar concerning the new TB drugs: Brian_Chong 2017 New TB drugs. TB drug monographs :  up-to-date clinical profiles of TB drugs including guidance on … Continue reading

Posted in Infectious diseases, Module- Mycobacteria, Mycobacteria tuberculosis | Tagged | Leave a comment

Zika transmission prevention not just for men- updated WHO guidance

Originally posted on AIMED – Let's talk about antibiotics:
The World Health Organization (WHO) has strengthened its advice on preventing sexual transmission of the Zika virus. The interim guidance report recommends that both men AND women practice safe sex for six…

Posted in Viruses | Tagged | Leave a comment

BCG vaccine – more than just protection from childhood tuberculosis

This is a useful BCG systematic review concerning childhood protection against TB- worth reading in detail. Longterm BCG protection into adulthood – vaccine efficacy (VE) 10-19 years post BCG was 58% (95% CI 27 to 76) p=0·002 and there was still a non-significant … Continue reading

Posted in Module- Mycobacteria, Mycobacteria tuberculosis, Public health | Tagged | 1 Comment

Molecular microbiology – recent tutorial references and resources

Basics DNA extraction – essential first step. Quantity of DNA obtained can be assayed spectrophotometrically. Reverse transcriptase step – for detection of RNA viruses Nucleic acid amplification –  know how PCR works! This PCR animation is easy to understand.  Many other … Continue reading

Posted in Med Micro topics-advanced, Microbiology, PNG | Tagged | Leave a comment

Metapneumovirus (hMPV) – bug of the week

Human-metapneumovirus-sept-2016-path-north summary sheet. See also this local case reports of severe pneumonia due to hMPV.  Includes discussion of Hunter New England region, NSW,  Australia epidemiology and current knowledge / research in to hMPV. Note the change to taxonomy that has occurred in … Continue reading

Posted in Module-Respiratory infections, Module-virology, Viruses | Tagged , | Leave a comment

Adenovirus – bug of the week

Adenovirus overview -2016-path-north; Prepared for our weekly pathology teaching round by one of our registrars. Reference CDC Adenovirus site Image credit: http://www.daviddarling.info/encyclopedia/A/adenovirus_infection.html  

Posted in Module-virology, Viruses | Tagged , | Leave a comment

Severe primary dengue- recent case and discussion

Guest posting from our Infectious Diseases advanced trainee, Dr Milton Micallef. ID meeting-presentation-dengue-dhf-and-dss Sept 2016 N.B. For an update on dengue viral vaccines (very promising work and at least one tetravalent vaccine in use), see WHO Dengue Vaccine Research page. Excellent … Continue reading

Posted in Infectious diseases, Module-virology, Viruses | Tagged | Leave a comment

Endemic Hepatitis E in Oz (and elsewhere) – update from Prof Josh Davis

Guest posting: A/Prof Josh Davis, Infectious Diseases Physician, John Hunter Hospital, NSW, Principal  Research Fellow, Menzies School of Health Research, NT, Australia. Another excellent presentation from Josh.  HEV talk ASID Annual Scientific Meeting 2016_Davis.  An essential topic for ID and Pathology post-grads! References (both … Continue reading

Posted in Med Micro topics-advanced, Module-virology, Viruses | Tagged | Leave a comment

What adverse fetal outcomes are associated with dengue in pregnancy?

Guest posting: Dr Ayesha Akram, Microbiology Registrar, Pathology North, NSW.  Prematurity and low birth weight are important causes of neonatal death and despite increasing awareness of the importance of these adverse pregnancy outcomes, the causes remains unknown on many occasions. … Continue reading

Posted in Module-virology, Viruses | Tagged , | Leave a comment