1. Acute meningitides – CNS infection cases Ferguson 2017 acute

• Acute bacterial meningitis – new treatment guidelines for PNG – Editorial PNGMJ 2012- Chloramphenicol replaced by ceftriaxone.

• Acute community-acquired meningitis and encephalitis – review 2002 MJA

• Primary amoebic meningoencephalitis (childhood) in QLD – review 2016 MJA
• See this link for an animation of PCR

2. Chronic meningitis and encephalitis  –  Encephalitis and chronic meningitis Ferguson 2017

See also this posting concerning cryptococcal antigen detection for HIV patients.

Potential viva questions (practice with each other!):

• What are the causes of acute meningitis in adults … in children  … in neonates
• What are the typical CSF findings in viral m … bacterial m.
• What is a parameningeal focus and explain what CSF findings might be expected
• Interpret this CSF picture – e.g one of the cases above
• Discuss the laboratory diagnosis of cryptococcal meningitis
• Discuss the lab dx of TB meningitis
• What are viral envelopes made of ? Contrast the properties of enveloped and non-enveloped viruses.
• Describe the causes of chronic meningitis